which of the following is true about deep lesioning

Pre-( a-c ) and postradiofrequency lesioning ( d-f ) in patient 2. a-c... | Download Scientific DiagramCOVID-19 is an emerging and rapidly evolving situation. Account name Save an appointment to archive E-mail citation Add to Collections Add to My Bibliography Your search saved Create a file for external dating management software Your RSS Feed Full text links Actions Share Page navigation Deep brain stimulators used for lesions: principle test Membership Deep brain stimulators used for lesions: principle test Authors Membership Summary Objective: Patients with deep brain stimulator electrodes implanted chronic (DBS) may find complications that require hardware removal. We evaluate the safety and effectiveness of the use of implanted DBS electrodes to create a therapeutic lesion before removal. Methods: Revision or removal of DBS electrodes was required in two patients who had previously been implanted by DBS. We performed a series of in vitro experiments to confirm that DBS electrodes could be used to generate radiofrequency lesions and to evaluate the relationship between the radiofrequency parameters and the size of the lesion. With this information, and with the approval of the hospital ethics review board, implanted electrodes were used to create incremental radiofrequency lesions in the talamo in one patient and in the sub-talmic core in another. The procedures were performed under local anesthesia with contiguous DBS lead contacts connected to the active and reference sites of the RF generator to create a bipolar lesion. Results: A 51-year-old man with essential tremor and a thalamic DBS requires repeated battery changes secondary to the demands of tolerance and high tension. Instead of replacing the battery, a radiofrequency thalamotomy was performed using the existing left DBS electrode. In the 6-month follow-up examination, the successful injury provided almost complete tremor control. A second patient, a 50-year-old man with Parkinson's disease who had undergone deep bilateral sub-almic brain stimulation, developed skin erosion over DBS hardware. A sub-talamic core lesion was performed through the right DBS electrode. The position and size of the lesion were confirmed with magnetic resonance. Conclusion: The lesions can be done through chronically implanted DBS electrodes in a safe and qualified way and can produce therapeutic benefits. Similar articles Cited by 5 articles Types of publication MeSH Terms Related information Link Out - more resources Full Text SourcesOther Literature SourcesMedicalNCBI Literacy Resources National Library of Medicine

Parkinson's diseaseParkinsonIdiopathy with Parkinson's disease: Deep brain stimulation and injury When we refer to 'surgery' in Parkinson's disease, it usually refers to deep brain stimulation (DBS). Deep brain stimulation involves placing a wire with electrodes at its tip in one of the three target sites in the brain - the talamo, the pallidus globus or the subtalmic core. A few days after connecting to an implantable pulse generator (IPG). This small unit is inserted under the skin on the chest wall. When IPG turns on the electric pulses stimulate the target area and cause a change in Parkinsonian symptoms. Before introducing DBS in the 1980s, the only available operation for Parkinson's disease meant selectively damaging certain cells in the thalamus and gobus pallidus called 'lesioning'. Although this sometimes relieved the symptoms the damage was irreversible and the operation was risky. With DBS you can check the insertion of the electrodes to confirm that they have been properly sidated and there are more opportunities to 'fine the adjustment' through the IPG. The technical advances that have made this operation possible have been the development of computed tomography and MRI that allow the surgeon to locate the target site with great precision. Although it is not essential, electrodes are usually inserted with the awake patient so they can provide evidence that the target has been reached. For several of the people interviewed who had not had the operation, the possibility of being awake while their brain was being manipulated was enough reason for them to dismiss the very idea of submitting it. As Humphrey said, "You see things on paper sometimes about an operation that involves electrodes in the brain, which requires open-head surgery without anesthesia. So I don't want to have that much, thank you very much. I prefer to have Parkinson's frankness." Helen says nothing on earth will persuade her to submit to DBS. Helen says nothing on earth will persuade her to submit to DBS. Peter had been fired at the beginning for seeing someone whose operation was unsuccessful, but then he saw... Peter had been fired at the beginning for seeing someone whose operation was unsuccessful, but then he saw... Khadim describes how the caregivers decided to offer him the DBS operation. Khadim describes how the caregivers decided to offer him the DBS operation. Joe explains what they told him about the operation before he accepted and why he agreed to have it. Joe explains what they told him about the operation before he accepted and why he agreed to have it. Stephen came to the point where DBS seemed to be the only choice. Stephen came to the point where DBS seemed to be the only option.... they said, "Look that we want to try a range of different drugs in you because we have to try, so many medicines in you without obviously hurting you, but as many drugs as we can in you to see if something is going to work on you, and then if it's not beyond the line, we'll do you an operation." Khadim describes what he felt to the prospect that he would not survive the operation. Khadim describes what he felt to the prospect that he would not survive the operation. Andrew had two DBS operations in the 1990s and remembers listening to the doctors talking about what... Andrew had two DBS operations in the 1990s and remembers listening to the doctors talking about the... Joe explains why it was necessary to be awake during the operation. Joe explains why it was necessary to be awake during the operation. Stephen was surprised when the effects of stimulation became evident during the operation. Stephen was surprised when the effects of stimulation became evident during the operation. ...If when they turned the stimulator into how interesting I noticed it was that I felt that this explosion of energy was going through me, it was like, I felt a lot more awake, like when I was awake before the operation was like a tired kind of waking up, if that makes sense, but I had one, like a shake, a shaking of life pumped through me and one of the things I didn't mention was like, although I was told to move Khadim. Khadim reminds surgeons to adjust the position of electrodes during the operation. Stephen was happy after the operation. Stephen was happy after the operation. Joe realized almost immediately that the operation had been a success. He explains some of the... Joe almost realized that the operation had been a success. He explains some of the... Elisabet notes changes from the DBS, including a new capacity found to sleep at night,...Elisabet notes changes from the DBS, including a new ability to sleep at night,... Joe compares his own improvement to that of other people he sees in the neurological outpatient... Joe compares his own improvement to that of other people he sees in the neurological outpatient... Stephen could reduce the amount of medication he takes. Stephen could reduce the amount of medication he takes. I don't take many pills and the object of the operation was also, the main thing was to stop my tremor that they did, but it was also to limit the amount of pills I was taking because I felt like, if I was scared, I rattle, as I was taking so many pills and I've always been against taking drugs and I'll only take drugs when I really have to take drugs because I think drugs are more addicted Andrew discovered the importance of his pulse generator. Andrew discovered the importance of his pulse generator when the wrong scenario was accidentally... The box controls the amptitude, voltage, polarity. It's about ten different things that he does and I have a good working relationship with the technician and he, if I feel like it's a bit of trembling, I'm getting a bit of trembling. I say, "I can find myself." Okay. I'm going across, he's out, "Oh, hey, how are you?" Two minutes, readjust and back away. No appointment, alone. It worked really well. I've kept it under control. When his generator was switched off during a hospital exam Stephen realized how... When his generator was switched off during a hospital exam Stephen realized how... Joe's condition has gradually deteriorated since his operation, and sometimes it's found... Joe's condition has gradually deteriorated since his operation, and sometimes it's found... Gina was turned off when she offered to donate her eggs. Gina was turned off when she offered to donate her eggs. Stephen thought people would change their opinions about stem cell research if they themselves... Stephen thought people would change their opinions about stem cell research if they themselves... Neil felt he had been very lucky to be included in the GDNF trial. Neil felt he had been very lucky to be included in the GDNF trial. Neil and the others in him were disappointed when the GDNF trial was suspended. Neil and the others in him were disappointed when the GDNF trial was suspended. Last revision May 2017. Last update May 2017. About usPolicies

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